3-[2-[(二甲基氨基)甲基]-1-羟基环己基]-苯酚盐酸盐(1:1)合成路线 (共 2 条)
反应条件
hydrogenchloride in isopropyl alcohol T=25°C; Cooling with ice;
参考文献
Syntrix Biosystems, Inc.; Zebala, John A.
Patent: US2013/11444 A1, 2013 ;
Location in patent: Paragraph 0212 ;
反应条件
1: sodium hydroxide / water / 0.25 h / 20 °C 2: diisobutylaluminium hydride / toluene / 23 h / |Cooling with ice; |Inert atmosphere; |Reflux 3: hydrogenchloride / isopropyl alcohol / 25 °C / |Cooling with ice View Scheme
参考文献
Syntrix Biosystems, Inc.; Zebala, John A.
Patent: US2013/11444 A1, 2013 ;