N-(4-溴丁基)氨基甲酸叔丁酯合成路线 （共 9 条）
反应条件
carbon tetrabromide; triphenylphosphine in tetrahydrofuran 3 h; Inert atmosphere;
参考文献
Simonin, Jonathan; Vernekar, Sanjeev Kumar V.; Thompson, Andrew J.; Hothersall, J. Daniel; Connolly, Christopher N.; Lummis, Sarah C.R.; Lochner, Martin
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 1151 - 1155
反应条件
triphenylphosphine in dichloromethane
参考文献
Kubo, Keiji; Miyawaki, Toshio; Kawamura, Masaki
Patent: US2003/187023 A1, 2003 ;
反应条件
1: 5-bromovaleric acid chloride With sodium azide; N-benzyl-N,N,N-triethylammonium chloride in toluene T=60 - 80°C; Curtius rearrangement; 1.25 h; 2: tert-butyl alcohol in toluene T=20°C;
参考文献
Bianco, Armandodoriano; Bonadies, Francesco; Napolitano, Raffaella; Ortaggi, Giancarlo
Organic Preparations and Procedures International, 2004 , vol. 36, # 2 p. 141 - 149
反应条件
lithium hydroxide in tetrahydrofuran; water T=20°C; Decarboxylation; 3 h;
参考文献
Berree, Fabienne; Bazureau, Jean-Pierre; Michelot, Gwendal; Le Corre, Maurice
Synthetic Communications, 1999 , vol. 29, # 15 p. 2685 - 2693
反应条件
sodium hydroxide in dichloromethane; water
参考文献
Henig, Joerg; Mamedov, Ilgar; Fouskova, Petra; Toth, Eva; Logothetis, Nikos K.; Angelovski, Goran; Mayer, Hermann A.
Inorganic Chemistry, 2011 , vol. 50, # 14 p. 6472 - 6481
反应条件
1: tetrahydrofuran / 1 h 2: TEA / CH2Cl2 / 2 h / cooling 3: 126 mg / LiBr / acetone; CH2Cl2 / 5 h View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 2, , # 5 p. 923 - 927
反应条件
1: t-BuOK / dimethylformamide / 1 h / 60 °C 2: 91 percent / LiOH / tetrahydrofuran; H2O / 3 h / 20 °C View Scheme
参考文献
Synthetic Communications, , vol. 29, # 15 p. 2685 - 2693
反应条件
lithium bromide in dichloromethane; acetone 5 h;
参考文献
Kim, Tae Woo; Park, Jung-hyun; Hong, Jong-In
Journal of the Chemical Society, Perkin Transactions 2, 2002 , # 5 p. 923 - 927
反应条件
potassium tert-butylate in N,N-dimethyl-formamide T=60°C; Alkylation; cyclization; 1 h;
参考文献
Berree, Fabienne; Bazureau, Jean-Pierre; Michelot, Gwendal; Le Corre, Maurice
Synthetic Communications, 1999 , vol. 29, # 15 p. 2685 - 2693
