反应条件
1: 74 percent / dimethylformamide / 2 h / 120 °C
2: 88 percent / potassium carbonate / dimethylformamide / 1 h / 60 °C
3: 85 percent / hydrochloric acid / 1 h / 60 °C
4: 78 percent / pyridine / acetonitrile / 16 h / Ambient temperature
5: 54 percent / 4-(dimethylamino)pyridine / acetonitrile / 16 h / Ambient temperature
View Scheme
参考文献
Kanaoka, Yoshitomo; Ikeuchi, Yoshihiro; Kawamoto, Tetsuji; Bessho, Kiyoshi; Akimoto, Naoshige; Mikata, Yuji; Nishida, Mamiko; Yano, Shigenobu; Sasaki, Takuma; Yoneda, Fumio
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 3 p. 301 - 314
