(2-苯基-1,3-噻唑-4-基)乙腈合成路线 （共 8 条）
反应条件
in ethyl acetate; acetonitrile
参考文献
Nissan Chemical Industries, Ltd.
Patent: US6063734 A1, 2000 ;
参考文献
Khilya,V.P. et al.
Journal of Organic Chemistry USSR (English Translation), 1973 , vol. 9, p. 2580 - 2586
Zhurnal Organicheskoi Khimii, 1973 , vol. 9, p. 2561 - 2567
反应条件
2: ethanol View Scheme
参考文献
Huntress; Pfister
Journal of the American Chemical Society, 1943 , vol. 65, p. 1667,1669
参考文献
Huntress; Pfister
Journal of the American Chemical Society, 1943 , vol. 65, p. 1667,1669
反应条件
sodium azide in N,N-dimethyl-formamide
T=120 - 130°C; 7 h;
参考文献
Madronero; Sanchez Insua; Del Rio; Vidal
European Journal of Medicinal Chemistry, 1974 , vol. 9, # 4 p. 445 - 448
反应条件
1: HCl, BF3-Et2O
2: Et3N
View Scheme
参考文献
Khilya,V.P. et al.
Journal of Organic Chemistry USSR (English Translation), 1973 , vol. 9, p. 2580 - 2586
Zhurnal Organicheskoi Khimii, 1973 , vol. 9, p. 2561 - 2567
反应条件
1: HCl, BF3-Et2O
2: Et3N
3: aq. NaOH / ethanol
View Scheme
参考文献
Khilya,V.P. et al.
Journal of Organic Chemistry USSR (English Translation), 1973 , vol. 9, p. 2580 - 2586
Zhurnal Organicheskoi Khimii, 1973 , vol. 9, p. 2561 - 2567
反应条件
1: HCl, BF3-Et2O
2: Et3N
3: aq. NaOH / ethanol
4: K2CO3 / acetone
View Scheme
参考文献
Khilya,V.P. et al.
Journal of Organic Chemistry USSR (English Translation), 1973 , vol. 9, p. 2580 - 2586
Zhurnal Organicheskoi Khimii, 1973 , vol. 9, p. 2561 - 2567
