1: 99 percent / 2,6-lutidine, Et3N / CH2Cl2 / 5 h / -78 °C 2: 1.) Bu3SnH, AIBN, 2.) I2 / 1.) benzene, 90 deg C, 1 h, 2.) CH2Cl2, 0 deg C 3: 56 percent / LiI / pyridine / 16 h / 130 °C 4: 1.) EDS, DMAP, DMAP*HCl, 2.) i-Pr2NEt, <(2-furyl)3P>2PdCl2 / 1.) CH2Cl2, room temperature, 5 h, 2.) THF, DMF, room temperature, 7 h 5: 90 percent / TBAF, AcOH / tetrahydrofuran / 3 h / 0 °C 6: 71 percent / HF*pyr, pyridine / tetrahydrofuran / Ambient temperature View Scheme