2,4-二氨基嘧啶-5-腈合成路线 (共 14 条)
反应条件
nickel monoaluminide in formic acid T=120°C; 1.5 h;
参考文献
Stuart; Paterson; Roth; Aig
Journal of Medicinal Chemistry, 1983 , vol. 26, # 5 p. 667 - 673
反应条件
Raney Nickel in water 3 - 4 h; Reflux;
参考文献
Karoli, Tomislav; Mamidyala, Sreeman K.; Zuegg, Johannes; Fry, Scott R.; Tee, Ernest H.L.; Bradford, Tanya A.; Madala, Praveen K.; Huang, Johnny X.; Ramu, Soumya; Butler, Mark S.; Cooper, Matthew A.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 7 p. 2428 - 2433
参考文献
Chatterjee; Anand
Journal of Scientific and Industrial Research, 1958 , vol. 17 B, p. 63,68
反应条件
hydrogenchloride; acetic acid in water
参考文献
Burroughs Wellcome Co.
Patent: US4568744 A1, 1986 ;