2-氯-3-哌嗪-1-基-喹噁啉合成路线 （共 4 条）
反应条件
sodium carbonate in butan-1-ol T=20°C; 22 h; Reflux;
参考文献
Chandra Sekhar, Kondapalli Venkata Gowri; Rao, Vajja Sambasiva; Deuther-Conrad, Winnie; Sridhar, Divya; Nagesh, Hunsur Nagendra; Kumar, Vellas Sreedhar; Brust, Peter; Kumar, Muthyala Murali Krishna
Medicinal Chemistry Research, 2013 , vol. 22, # 4 p. 1660 - 1673
反应条件
1: ethanol / 6 h / |Reflux 2: trichlorophosphate / |Reflux 3: sodium carbonate / butan-1-ol / 22 h / 20 °C / |Reflux View Scheme
参考文献
Chandra Sekhar, Kondapalli Venkata Gowri; Rao, Vajja Sambasiva; Deuther-Conrad, Winnie; Sridhar, Divya; Nagesh, Hunsur Nagendra; Kumar, Vellas Sreedhar; Brust, Peter; Kumar, Muthyala Murali Krishna
Medicinal Chemistry Research, 2013 , vol. 22, # 4 p. 1660 - 1673
反应条件
1: trichlorophosphate / |Reflux 2: sodium carbonate / butan-1-ol / 22 h / 20 °C / |Reflux View Scheme
参考文献
Chandra Sekhar, Kondapalli Venkata Gowri; Rao, Vajja Sambasiva; Deuther-Conrad, Winnie; Sridhar, Divya; Nagesh, Hunsur Nagendra; Kumar, Vellas Sreedhar; Brust, Peter; Kumar, Muthyala Murali Krishna
Medicinal Chemistry Research, 2013 , vol. 22, # 4 p. 1660 - 1673
反应条件
triethylamine in dichloromethane
T=0 - 20°C;
参考文献
BIOVITRUM AB
Patent: WO2004/9586 A1, 2004 ;
Location in patent: Page 51 ;
WO 2004/009586 A1
