7-溴-1,2,3,4-四氢环戊二烯并[b]吲哚合成路线 (共 5 条)
反应条件
1: With pyridine; bromine in dichloromethane T=-20°C; 30 h; 2: With acetic acid; zinc in tetrahydrofuran; dichloromethane T=-78 - 20°C;
参考文献
Journal of Heterocyclic Chemistry, , vol. 40, # 2 p. 289 - 295
反应条件
tert.-butyl lithium; potassium hydride in diethyl ether T=-78°C; 0.166667 h;
参考文献
Tetrahedron Letters, , vol. 44, # 4 p. 689 - 692
反应条件
in ethanol 4 h; Heating;
参考文献
Harrison, Carrie-Ann; Jackson, P. Mark; Moody, Christopher J.; Williams, Jonathan M. J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 9 p. 1131 - 1136
反应条件
1.1: 44 percent / 1.5 h / 125 °C 2.1: Br2; pyridine / CH2Cl2 / 30 h / -20 °C 2.2: 46 percent / Zn AcOH / tetrahydrofuran; CH2Cl2 / -78 - 20 °C View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 40, # 2 p. 289 - 295
反应条件
1.1: 44 percent / 1.5 h / 125 °C 2.1: Br2; pyridine / CH2Cl2 / 30 h / -20 °C 2.2: 46 percent / Zn AcOH / tetrahydrofuran; CH2Cl2 / -78 - 20 °C View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 40, # 2 p. 289 - 295