(R,R)-La-linked-BINOL Complex in ethylene glycol dimethyl ether T=4°C; Michael addition; 85 h;

Al-Li-(R,R')-2,2'-dihydroxy-1,1'-binaphthyl in tetrahydrofuran 72 h; various time, catalysts; Product distribution;

piperidine; 5-[(2S)-pyrrolidine-2-yl]-1H-tetrazole in chloroform T=20°C; Michael condensation; 72 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;

hexafluoroisopropyl alcohol; (S)-N-(2-pyrrolidylmethyl)-N,N,N-trimethylammonium hydroxide in toluene amounts of chiral additive and 1,1,1,3,3,3-hexafluoro-2-propanol were varied; Product distribution;