(S)-4-苄氧甲基-2,2-二甲基-1,3-二氧戊环合成路线 （共 25 条）
反应条件
sodium hydride in tetrahydrofuran; N,N-dimethyl-formamide T=0 - 20°C; 4 h;
参考文献
Fujifilm Corporation
Patent: EP1795208 A1, 2007 ;
Location in patent: Page/Page column 13-14 ;
反应条件
potassium hydroxide; 18-crown-6 ether in tetrahydrofuran T=20°C; benzylation;
参考文献
Xia, Jie; Hui, Yong-Zheng
Chemical and Pharmaceutical Bulletin, 1999 , vol. 47, # 11 p. 1659 - 1663
反应条件
sodium hydroxide in water; N,N-dimethyl-formamide
反应条件
1: 1.) IO4- resin, 2.) BH4- resin 2: NaH View Scheme
参考文献
Journal of the American Chemical Society, , vol. 120, # 2 p. 457 - 458
反应条件
1: 3-benzyloxypropyleneoxide With polymer-supported Co(III)-(R,R)-salen ligand; water T=20°C; 4 h; 2: 2,2-dimethoxy-propane With toluene-4-sulfonic acid Title compound not separated from byproducts;
参考文献
Angewandte Chemie - International Edition, , vol. 45, # 8 p. 1309 - 1312
反应条件
ethylene glycol dimethyl ether; naphthalene; sodium Erwaermen des Reaktionsgemisches mit Benzylbromid;
参考文献
Journal of the American Chemical Society, , vol. 63, p. 3244,3245
反应条件
1: 2,2-dimethyl-1,3-dioxolane-4-methanol With sodium hydride in N,N-dimethyl-formamide; mineral oil 0.666667 h; Cooling with ice; 2: benzyl bromide in N,N-dimethyl-formamide; mineral oil T=20°C; 2 h;
参考文献
European Journal of Organic Chemistry, , # 20 p. 4311 - 4318
反应条件
1: LiAlH4 / tetrahydrofuran / 2 h / -50 °C 2: p-TsOH / acetone / 10 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 52, # 44 p. 13919 - 13932
反应条件
1: 1.) O3, 2.) Me2S / 1.) MeOH. -78 deg C, 2.) MeOH, RT, 5 h 2: NaBH4 / methanol / 3 h / Ambient temperature 3: LiAlH4 / tetrahydrofuran / 2 h / -50 °C 4: p-TsOH / acetone / 10 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 52, # 44 p. 13919 - 13932
反应条件
hydrogen cation in acetone
参考文献
Tetrahedron Letters, , vol. 29, # 10 p. 1157 - 1160
