(S)-4-苄氧甲基-2,2-二甲基-1,3-二氧戊环合成路线 （共 25 条）
反应条件
palladium monocarbide in ethyl acetate
参考文献
Daiso Co., Ltd.
Patent: US6124479 A1, 2000 ;
反应条件
1: 3N HCl / 65 °C 2: PPh3, diethylazodicarboxylate / tetrahydrofuran / Heating View Scheme
参考文献
Takano, Seiichi; Goto, Emiko; Hirama, Michiyasu; Ogasawara, Kunio
Heterocycles, 1981 , vol. 16, # 3 p. 381 - 385
反应条件
1: 91 percent / 1N H2SO4 / 1 h / 90 °C 2: 64.5 percent / pyridine / CHCl3 / Ambient temperature View Scheme
参考文献
Nelson,W.L. et al.
Journal of Organic Chemistry, 1977 , vol. 42, p. 1006 - 1012
反应条件
1: 1N aq. HCl
2: 94 percent / Et3N, DMAP
View Scheme
参考文献
Hirth; Barner
Helvetica Chimica Acta, 1982 , vol. 65, # 3 p. 1059 - 1084
反应条件
1: 95 percent / 70percent AcOH / 0.5 h / 65 °C
2: 54 percent / pyridine
3: 29 percent / NaH / dimethylsulfoxide / Ambient temperature
4: 1.) AcOH, 2.) NaOMe / 1.) H2O, 2.) MeOH
View Scheme
参考文献
Wickberg
Acta Chemica Scandinavica (1947-1973), 1958 , vol. 12, p. 1187,1195
