1,2,3,4-四氢-9H-吡啶[3,4-B]并吲哚合成路线 （共 42 条）
反应条件
1: 82 percent / 1 M KOH / H2O / 1 h / pH 4 2: 88 percent / conc. HCl, H2O / 0.5 h / Heating View Scheme
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 42, # 7 p. 433 - 441
反应条件
formaldehyd; sulfuric acid Erhitzen des Reaktionsprodukts mit wss. H2SO4;
参考文献
Chemische Berichte, , vol. 63, p. 2102,2106
反应条件
in Phosphatpuffer (pH 6.2);
参考文献
Bulletin de la Societe Chimique de France, , p. 230,234
反应条件
in tetrahydrofuran 1 h;
参考文献
Moehrle, Hans; Schillings, Peter
Monatshefte fuer Chemie, 1987 , vol. 118, p. 477 - 484
反应条件
1: 67 percent / Na2CO3 / benzene / 18 h / Heating 2: 73 percent / H2 / 10percent Pd-C / ethanol / 1500.1 Torr / Ambient temperature 3: 77 percent / HgO, EDTA / aq. ethanol / 1 h / 100 °C 4: MnO2 / benzene / 7.5 h View Scheme
参考文献
Moehrle, Hans; Kamper, Christa; Schmid, Renate
Archiv der Pharmazie (Weinheim, Germany), 1980 , vol. 313, # 12 p. 990 - 995
反应条件
1: ethanol / 72 h / |Reflux 2: potassium permanganate / acetone / 3 h / |Reflux View Scheme
参考文献
Richers, Matthew T.; Deb, Indubhusan; Platonova, Alena Yu.; Zhang, Chen; Seidel, Daniel
Synthesis (Germany), 2013 , vol. 45, # 13 art. no. SS-2013-C0210-FA, p. 1730 - 1748
反应条件
palladium 10 on activated carbon in para-xylene T=145°C; 72 h;
参考文献
Peng, Jing; Chen, Chao; Wang, Yong; Lou, Zhenbang; Li, Ming; Xi, Chanjuan; Chen, Hui
Angewandte Chemie - International Edition, 2013 , vol. 52, # 29 p. 7574 - 7578
Angew. Chem., 2013 , vol. 125, # 29 p. 7722 - 7726,5
反应条件
trichloroisocyanuric acid; triethylamine 16 h; Ambient temperature;
参考文献
Haffer, Gregor; Nickisch, Klaus; Tilstam, Ulf
Heterocycles, 1998 , vol. 48, # 5 p. 993 - 998
反应条件
1: 98 percent / CH2Cl2 / 0 - 20 °C 2: 96 percent / N-cetyl-N,N,N-trimethylammonium bromide; NaOH / CH2Cl2 / cooling 3: 40 percent / CF3SO3NO2 / CH2Cl2 / -50 - 0 °C 4: 90 percent / NaOH / ethanol; H2O / 1 h / 20 °C View Scheme
参考文献
Forte, Barbara; Lombardi-Borgia, Andrea; Papeo, Gianluca
Synthetic Communications, 2003 , vol. 33, # 21 p. 3707 - 3716
反应条件
potassium carbonate in water; isopropyl alcohol T=20°C; 17 h;
参考文献
Kikuchi, Chika; Ando, Takashi; Watanabe, Takashi; Nagaso, Hiroshi; Okuno, Masayo; Hiranuma, Toyokazu; Koyama, Masao
Journal of Medicinal Chemistry, 2002 , vol. 45, # 11 p. 2197 - 2206
