(2alpha,3xi,5beta,10beta,13alpha)-4,10-二乙酰氧基-13-{[(2R,3S)-3-(苯甲酰基氨基)-2-{[二甲基(2-甲基-2-丙基)硅烷基]氧基}-3-苯基丙酰基]氧基}-1-羟基-9-氧代-5,20-环氧紫杉-6,11-二烯-2-基苯甲酸酯合成路线 （共 5 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane T=40°C; 4 h;
参考文献
Tetrahedron, , vol. 53, # 10 p. 3441 - 3456
反应条件
1: 99 percent / imidazole / dimethylformamide 2: 1.) Tf2O, 2.) DBU / 1.) pyridine, 25 deg C, 2.) 25 deg C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 14 p. 1941 - 1944
反应条件
1: 99 percent / imidazole / dimethylformamide 2: 1.) Tf2O, 2.) DBU / 1.) pyridine, 25 deg C, 2.) 25 deg C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 14 p. 1941 - 1944
反应条件
1: 92 percent / 4-dimethylaminopyridine / CH2Cl2 / 2.5 h / Ambient temperature 2: 86 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / CH2Cl2 / 4 h / 40 °C View Scheme
参考文献
Tetrahedron, , vol. 53, # 10 p. 3441 - 3456
反应条件
trifluoromethylsulfonic anhydride; 1,8-diazabicyclo[5.4.0]undec-7-ene 1.) pyridine, 25 deg C, 2.) 25 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 14 p. 1941 - 1944
