4-(2-氯-1-羟基乙基)苯甲腈合成路线 （共 2 条）
反应条件
n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1.5 h;
参考文献
Haak, Robert M.; Berthiol, Florian; Jerphagnon, Thomas; Gayet, Arnaud J. A.; Tarabiono, Chiara; Postema, Christiaan P.; Ritleng, Vincent; Pfeffer, Michel; Janssen, Dick B.; Minnaard, Adriaan J.; Feringa, Ben L.; De Vries, Johannes G.
Journal of the American Chemical Society, 2008 , vol. 130, # 41 p. 13508 - 13509
反应条件
[Ir(η5-C5Me5)(C6H4-2-CH2NHCH3)(NCCH3)](PF6); potassium tert-butylate; bovine serum albumin in dimethyl sulfoxide; toluene T=20°C; pH=8.0; 6 h; aq. bufferInert atmosphereResolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Haak, Robert M.; Berthiol, Florian; Jerphagnon, Thomas; Gayet, Arnaud J. A.; Tarabiono, Chiara; Postema, Christiaan P.; Ritleng, Vincent; Pfeffer, Michel; Janssen, Dick B.; Minnaard, Adriaan J.; Feringa, Ben L.; De Vries, Johannes G.
Journal of the American Chemical Society, 2008 , vol. 130, # 41 p. 13508 - 13509
