2-氟-2-甲基丙二酸二乙酯合成路线 （共 10 条）
参考文献
Pattison,F.L.M. et al.
Canadian Journal of Chemistry, 1965 , vol. 43, p. 1700 - 1713
反应条件
disodium hydrogenphosphate; potassium dihydrogenphosphate; Trichoderma Viride T=40 - 41°C; 6 h; pH=7.3;
参考文献
Kitazume, Tomoya; Sato, Takehiko; Ishikawa, Nobuo
Chemistry Letters, 1984 , p. 1811 - 1814
反应条件
N-fluorobislt;(trifluoromethyl)sulfonylgt;imide in chloroform-d1
T=-10°C;
参考文献
Singh, Sukhjinder; DesMarteau, Darryl D.; Zuberi, Sharique S.; Witz, Michael; Huang, Hsu-Nan
Journal of the American Chemical Society, 1987 , vol. 109, # 23 p. 7194 - 7196
反应条件
sodium hydride; N-fluoro-N-2,2-dimethylpropyl-p-toluenesulfonamide in tetrahydrofuran; toluene
Ambient temperature;
参考文献
Barnette, W. E.
Journal of the American Chemical Society, 1984 , vol. 106, # 2 p. 452 - 454
反应条件
in tetrahydrofuran; toluene
参考文献
E. I. Du Pont de Nemours and Company
Patent: US4479901 A1, 1984 ;
反应条件
sodium in ethanol
1 h; Heating;
参考文献
Ishikawa,N.; Takaoka,A.
Journal of Fluorine Chemistry, 1984 , vol. 25, p. 203
反应条件
3-F2I-4-Me-furazan in acetonitrile
T=0°C; 0.5 h;
参考文献
Sheremetev; Dmitriev; Konkina
Russian Chemical Bulletin, 2004 , vol. 53, # 5 p. 1130 - 1132
反应条件
1: 82 percent / conc. sulfuric acid / 1 h / Ambient temperature
2: ethanol / 0.5 h / Ambient temperature
3: 63 percent / conc. HCl / ethanol / 1 h / Ambient temperature
4: 74 percent / sodium / ethanol / 1 h / Heating
View Scheme
参考文献
Ishikawa,N.; Takaoka,A.
Journal of Fluorine Chemistry, 1984 , vol. 25, p. 203
反应条件
1: ethanol / 0.5 h / Ambient temperature
2: 63 percent / conc. HCl / ethanol / 1 h / Ambient temperature
3: 74 percent / sodium / ethanol / 1 h / Heating
View Scheme
参考文献
Ishikawa,N.; Takaoka,A.
Journal of Fluorine Chemistry, 1984 , vol. 25, p. 203
反应条件
1: 63 percent / conc. HCl / ethanol / 1 h / Ambient temperature
2: 74 percent / sodium / ethanol / 1 h / Heating
View Scheme
参考文献
Ishikawa,N.; Takaoka,A.
Journal of Fluorine Chemistry, 1984 , vol. 25, p. 203
