1: 4-nitro-3-bromophenol With potassium carbonate in N,N-dimethyl-formamide T=20°C; 0.333333 h; Inert atmosphere; 2: benzyl bromide in N,N-dimethyl-formamide T=20°C; Inert atmosphere;

1.1: sulfuric acid; sodium nitrate / water; ethanol / 20 - 30 °C / |Inert atmosphere 2.1: potassium carbonate / N,N-dimethyl-formamide / 0.33 h / 20 °C / |Inert atmosphere 2.2: 20 °C / |Inert atmosphere View Scheme

1: 2-mercapto benzoic acid With sodium hydride in N,N-dimethyl acetamide 2: 4-(benzyloxy)-2-bromo-1-nitrobenzene in N,N-dimethyl acetamide T=80°C; 1 h; 3: methyl iodide in N,N-dimethyl acetamide T=20°C; 45 h; Further stages.;

1: 2-mercapto benzoic acid With sodium hydride in N,N-dimethyl acetamide 2: 4-(benzyloxy)-2-bromo-1-nitrobenzene in N,N-dimethyl acetamide T=80°C; 1 h; 3: methyl iodide in N,N-dimethyl acetamide T=20°C; 45 h; Further stages.;