N-(3-甲基苯基)邻氨基苯甲酸合成路线 （共 10 条）
反应条件
copper(I) oxide; copper; potassium carbonate in 2-ethoxy-ethanol T=130°C; 24 h;
参考文献
Mei, Xuefeng; August, Adam T.; Wolf, Christian
Journal of Organic Chemistry, 2006 , vol. 71, # 1 p. 142 - 149
反应条件
1: With potassium hydroxide in ethanol; water T=20 - 100°C; Inert atmosphere; 2: With hydrogenchloride in water T=0°C; pH=2; Inert atmosphere;
参考文献
Adeniji, Adegoke O.; Twenter, Barry M.; Byrns, Michael C.; Jin, Yi; Chen, Mo; Winkler, Jeffrey D.; Penning, Trevor M.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 5 p. 2311 - 2323
反应条件
copper diacetate in isopropyl alcohol 6 h; Heating;
参考文献
Chalmers; Scholz; Topliss; Kolliniatis; Munro; Craik; Iskander; Stockigt
Journal of Medicinal Chemistry, 1993 , vol. 36, # 9 p. 1272 - 1277
反应条件
copper; potassium carbonate in pentan-1-ol Ullmann Condensation; 3 h; Reflux;
参考文献
Di Fusco, Massimo; Quintavalla, Arianna; Trombini, Claudio; Lombardo, Marco; Roda, Aldo; Guardigli, Massimo; Mirasoli, Mara
Journal of Organic Chemistry, 2013 , vol. 78, # 22 p. 11238 - 11246
反应条件
n-ethyl morpholine; copper diacetate in N,N-dimethyl-formamide T=145°C; 3 h;
参考文献
Kaltenbronn; Scherrer; Short; Jones; Beatty; Saka; Winder; Wax; Williamson
Arzneimittel-Forschung/Drug Research, 1983 , vol. 33, # 4 A p. 621 - 627
反应条件
1.1: palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl / toluene / 20 - 120 °C / Inert atmosphere 2.1: potassium hydroxide / ethanol; water / 20 - 100 °C / Inert atmosphere 2.2: 0 °C / pH 2 / Inert atmosphere View Scheme
参考文献
Adeniji, Adegoke O.; Twenter, Barry M.; Byrns, Michael C.; Jin, Yi; Chen, Mo; Winkler, Jeffrey D.; Penning, Trevor M.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 5 p. 2311 - 2323
反应条件
bei der Destillation;
参考文献
Ullmann; Bader
Justus Liebigs Annalen der Chemie, 1907 , vol. 355, p. 324
参考文献
Lehmstedt; Schrader
Chemische Berichte, 1937 , vol. 70, p. 838,845
Full Text Show Details
Gleu; Nitzsche
Journal fuer Praktische Chemie (Leipzig), 1939 , vol. <2> 153, p. 200,213
反应条件
trichlorophosphate in acetonitrile
3 h; Reflux;
参考文献
Di Fusco, Massimo; Quintavalla, Arianna; Trombini, Claudio; Lombardo, Marco; Roda, Aldo; Guardigli, Massimo; Mirasoli, Mara
Journal of Organic Chemistry, 2013 , vol. 78, # 22 p. 11238 - 11246
反应条件
trichlorophosphate
Erwaermen des Reaktionsprodukts mit wss.Salzsaeure;
参考文献
Lehmstedt; Schrader
Chemische Berichte, 1937 , vol. 70, p. 838,845
