4-溴-3,5-二羟基苯甲酸合成路线 (共 20 条)
反应条件
hydrogenchloride; bromine 2 h; Heating;
参考文献
Durola, Fabien; Hanss, David; Roesel, Pirmin; Sauvage, Jean-Pierre; Wenger, Oliver S.
European Journal of Organic Chemistry, 2007 , # 1 p. 125 - 135
反应条件
dihydrogen peroxide; sodium bromide; ethyl orthosilicate; gamma-aminopropyltriethoxysilane in 1,4-dioxane; phosphate buffer 19 h;
参考文献
Bennett, Stephanie M.; Tang, Ying; McMaster, Danielle; Bright, Frank V.; Detty, Michael R.
Journal of Organic Chemistry, 2008 , vol. 73, # 17 p. 6849 - 6852
参考文献
Justus Liebigs Annalen der Chemie, , vol. 164, p. 118
参考文献
Barfknecht; Nichols
Journal of medicinal chemistry, 1971 , vol. 14, # 4 p. 370 - 372
反应条件
potassium hydroxide beim Schmelzen;
参考文献
Barth; Senhofer
Justus Liebigs Annalen der Chemie, 1872 , vol. 164, p. 118
反应条件
potassium carbonate in acetone 12 h; Reflux;
参考文献
Saeed, Aamer; Qasim, Muhammad; Simpson, Jim
Acta Crystallographica Section C: Crystal Structure Communications, 2013 , vol. 69, # 7 p. 790 - 793
反应条件
potassium carbonate; dimethyl sulfate in acetone 24 h; RefluxInert atmosphere;
参考文献
Saeed, Aamer; Mahesar, Parvez Ali
Tetrahedron, 2014 , vol. 70, # 7 p. 1401 - 1407
反应条件
potassium carbonate in N,N-dimethyl-formamide T=0 - 20°C; 17 h;
参考文献
Negi, Shigeto; Shimizu, Toshikazu; Kuroda, Hiroshi; Shimomura, Naoyuki; Sasho, Manabu; Hoshino, Yorihisa; Kubota, Manabu
Patent: US2007/191613 A1, 2007 ;
Location in patent: Page/Page column 12 ;
参考文献
WELICHEM BIOTECH, INC.
Patent: US2005/59733 A1, 2005 ;
US 20050059733 A1
反应条件
2: (i) SOCl2, (ii) Li<AlH(OtBu)3> View Scheme
参考文献
Barfknecht; Nichols
Journal of medicinal chemistry, 1971 , vol. 14, # 4 p. 370 - 372