4-(2-Boc-氨乙基)哌啶合成路线 （共 4 条）
反应条件
hydrogenchloride; hydrogen; platinum(IV) oxide in methanol T=20°C; 18 h;
参考文献
GLAXO GROUP LIMITED
Patent: WO2004/87145 A2, 2004 ;
Location in patent: Page/Page column 31 ;
反应条件
1: 2-methyl-propan-2-ol / 12 h / 20 °C 2: 21.9 g / H2; AcOH / PtO2 / 96 h / 35 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 14 p. 4116 - 4126
反应条件
1: 46.9 g / ammonium chloride / H2O; methanol / Heating 2: 2-methyl-propan-2-ol / 12 h / 20 °C 3: 21.9 g / H2; AcOH / PtO2 / 96 h / 35 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 14 p. 4116 - 4126
反应条件
1: methanol 2: H2; AcOH / PtO2 / methanol View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 17 p. 2325 - 2330
