1: T=23°C; 7 h; 2: With potassium hydroxide in water T=23°C;
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; GARG, Neil K.; RAMGREN, Stephen D.; SILBERSTEIN, Amanda L.; QUASDORF, Kyle W.
Patent: WO2012/94622 A2, 2012 ;
Location in patent: Page/Page column 31-32 ;
1: With hydrogenchloride in water; ethyl acetate T=55°C; 2 h; 2: With sodium hydroxide in water; ethyl acetate pH=10; Product distribution / selectivity;
参考文献
Union Quimico Farmaceutica, S.A. (UQUIFA)
Patent: EP2163547 A1, 2010 ;
Location in patent: Page/Page column 11 ;