1-羟基-10-甲基-9(10H)-吖啶酮合成路线 (共 4 条)
反应条件
water; hydrogen iodide T=100°C; 24 h;
参考文献
Dubrovskiy, Anton V.; Larock, Richard C.
Journal of Organic Chemistry, 2012 , vol. 77, # 24 p. 11232 - 11256
反应条件
potassium carbonate in acetone Methylation; 3 h; Heating;
参考文献
Chen, Jun-Jie; Deady, Leslie W.; Mackay, Maureen F.
Tetrahedron, 1997 , vol. 53, # 37 p. 12717 - 12728
反应条件
1: 1,3-cylohexanedione With potassium carbonate in dimethyl sulfoxide T=20°C; Metallation; 1 h; 2: 1-methyl-2H-3,1-benzoxazine-2,4(1H)-dione in dimethyl sulfoxide T=110°C; Substitution; aromatization; 18 h;
参考文献
Copolla, Gary M.
Organic Preparations and Procedures International, 1999 , vol. 31, # 2 p. 225 - 227
反应条件
PPA; Polyphosphoric acid (PPA) 0.75 h; Heating;
参考文献
Hormi
Journal of Organic Chemistry, 1988 , vol. 53, # 4 p. 880 - 882