N-(1H-咪唑-2-基甲基)苯胺合成路线 （共 3 条）
反应条件
TAB-P in 1,2-dichloro-ethane
T=20°C; 3 h;
参考文献
Liao, Wenyan; Chen, Yunfeng; Liu, Yuxiu; Duan, Haifeng; Petersen, Jeffrey L.; Shi, Xiaodong
Chemical Communications, 2009 , # 42 p. 6436 - 6438
反应条件
sodium tetrahydroborate in methanol
2 h; Ambient temperature;
参考文献
Rovnyak, George C.; Ahmed, Syed Z.; Ding, Charles Z.; Dzwonczyk, Steven; Ferrara, Francis N.; Humphreys, W. Griffith; Grover, Gary J.; Santafianos, Dinos; Atwal, Karnail S.; Baird, Anne J.; McLaughlin, Lee G.; Normandin, Diane E.; Sleph, Paul G.; Traeger, Sarah C.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 1 p. 24 - 34
反应条件
1: methanol / 16 h / 55 - 60 °C
2: NaBH4 / methanol / 2 h / Ambient temperature
View Scheme
参考文献
Rovnyak, George C.; Ahmed, Syed Z.; Ding, Charles Z.; Dzwonczyk, Steven; Ferrara, Francis N.; Humphreys, W. Griffith; Grover, Gary J.; Santafianos, Dinos; Atwal, Karnail S.; Baird, Anne J.; McLaughlin, Lee G.; Normandin, Diane E.; Sleph, Paul G.; Traeger, Sarah C.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 1 p. 24 - 34
