5-硝基-1H-吲哚-1-甲酸叔丁酯合成路线 （共 5 条）
反应条件
4-(N,N-dimethlyamino)pyridine in tetrahydrofuran T=20°C; 0.583333 h; Inert atmosphere;
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 15 p. 6273 - 6277
反应条件
in various solvent(s) T=150°C; 0.0833333 h; microwave irradiation;
参考文献
F. Hoffmann-La Roche AG
Patent: EP2070899 A1, 2009 ;
Location in patent: Page/Page column 3; 4-5 ;
反应条件
1: NH2NH2*H2O / Pd-C / methanol / Heating 2: 85 percent / K2CO3 / methanol; H2O / 4 h / Heating View Scheme
参考文献
Chakrabarty, Manas; Kundu, Taraknath; Harigaya, Yoshihiro
Synthetic Communications, 2006 , vol. 36, # 14 p. 2069 - 2077
反应条件
hydrogen; palladium on activated charcoal in ethanol T=20°C; 6 h;
参考文献
Iyer, Pravin; Lucas, Matthew C.; Schoenfeld, Ryan Craig; Weikert, Robert James
Patent: US2009/247568 A1, 2009 ;
Location in patent: Page/Page column 36 ;
US 20090247568 A1
反应条件
hydrogen; palladium 10 on activated carbon in methanol T=20°C; 1.5 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: WO2008/113760 A2, 2008 ;
Location in patent: Page/Page column 92 ;
WO 2008/113760 A2
