3-氨基-4-氰基吡唑合成路线

参考文献

Da Settimo, Federico; Primofiore, Giampaolo; La Motta, Concettina; Taliani, Sabrina; Simorini, Francesca; Marini, Anna Maria; Mugnaini, Laura; Lavecchia, Antonio; Novellino, Ettore; Tuscano, Daniela; Martini, Claudia
Journal of Medicinal Chemistry, 2005 , vol. 48, # 16 p. 5162 - 5174

16617-46-23-氨基-4-氰基吡唑

159979-72-3

参考文献

Baraldi, Pier Giovanni; Cacciari, Barbara; Spalluto, Giampiero; Pineda De Las Infantas Y Villatoro, Maria Jose; Zocchi, Cristina; Dionisotti, Silvio; Ongini, Ennio
Journal of Medicinal Chemistry, 1996 , vol. 39, # 5 p. 1164 - 1171

17376-04-42-碘代乙基苯+

16617-46-23-氨基-4-氰基吡唑

159979-72-3

参考文献

Paira, Priyankar; Chow, Mun Juinn; Venkatesan, Gopalakrishnan; Kosaraju, Vamsi Krishna; Cheong, Siew Lee; Klotz, Karl-Norbert; Ang, Wee Han; Pastorin, Giorgia
Chemistry - A European Journal, 2013 , vol. 19, # 25 p. 8321 - 8330

115931-01-6N-[3-(3-氰基吡唑并[1,5-a]嘧啶-7-基)苯基]乙酰胺

参考文献

American Cyanamid Company
Patent: US4847256 A1, 1989 ;

137-43-9溴代环戊烷+

16617-46-23-氨基-4-氰基吡唑

30929-67-05-氨基-1-环戊基-1H-吡唑-4-甲腈+

122799-98-83-氨基-1-环戊醇-1H-吡唑-4-甲腈

参考文献

US2007/281949 A1, ;

Page/Page column 15-16 ;

137-43-9溴代环戊烷+

16617-46-23-氨基-4-氰基吡唑

122799-98-83-氨基-1-环戊醇-1H-吡唑-4-甲腈

参考文献

AMBIT BIOSCIENCES CORPORATION; CHAO, Qi; HADD, Michael, J.; HOLLADAY, Mark, W.; ROWBOTTOM, Martin
Patent: WO2012/30924 A1, 2012 ;
Location in patent: Page/Page column 163-164 ;
WO 2012/030924 A1

16617-46-23-氨基-4-氰基吡唑

122799-98-83-氨基-1-环戊醇-1H-吡唑-4-甲腈

参考文献

Chakrabarti, Jiban K.; Hotten, Terrence M.; Pullar, Ian A.; Tye, Nicholas C.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 12 p. 2573 - 2582

100-44-7苄基氯+

16617-46-23-氨基-4-氰基吡唑

91091-13-35-氨基-1-苄基-4-氰基吡唑+

122800-01-53-氨基-1-苄基-1H-吡唑-4-甲腈

参考文献

AMBIT BIOSCIENCES CORPORATION; CHAO, Qi; HADD, Michael, J.; HOLLADAY, Mark, W.; ROWBOTTOM, Martin
Patent: WO2012/30924 A1, 2012 ;
Location in patent: Page/Page column 147 ;
WO 2012/030924 A1

16617-46-23-氨基-4-氰基吡唑+

100-39-0溴化苄

122800-01-53-氨基-1-苄基-1H-吡唑-4-甲腈

参考文献

Da Settimo, Federico; Primofiore, Giampaolo; La Motta, Concettina; Taliani, Sabrina; Simorini, Francesca; Marini, Anna Maria; Mugnaini, Laura; Lavecchia, Antonio; Novellino, Ettore; Tuscano, Daniela; Martini, Claudia
Journal of Medicinal Chemistry, 2005 , vol. 48, # 16 p. 5162 - 5174

16617-46-23-氨基-4-氰基吡唑

122800-01-53-氨基-1-苄基-1H-吡唑-4-甲腈

参考文献

Chakrabarti, Jiban K.; Hotten, Terrence M.; Pullar, Ian A.; Tye, Nicholas C.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 12 p. 2573 - 2582