2,3-二氢-2-苯基-4(1H)-喹啉合成路线 （共 28 条）
反应条件
1: 68 percent / Et3N / (Ph3P)2PdCl2 / 24 h / 20 °C 2: 89 percent / p-toluenesulfonic acid / benzene / 48 h / 20 °C 3: aq. sodium hydroxide / ethanol / 40 h / 20 °C 4: phosphoric acid / acetic acid / 0.42 h / 90 °C View Scheme
参考文献
Tetrahedron, , vol. 53, # 39 p. 13397 - 13418
反应条件
1: 1 h / Ambient temperature 2: 2,6-lutidine / CH2Cl2; tetrahydrofuran / Ambient temperature 3: 96 percent / H2 / 10percent Pd-C / methanol / Ambient temperature View Scheme
参考文献
Synlett, , vol. 1997, # 3 p. 313 - 315
反应条件
1: 65 percent / 15percent aq. NaOH / ethanol / 24 h / Ambient temperature 2: 67 percent / HOAc, orthophosphoric acid / 0.33 h / 100 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 7 p. 1155 - 1162
反应条件
phosphomolybdic acid supported on silica in ethanol 18 h; RefluxInert atmosphere;
参考文献
Sakirolla, Raghavendra; Yaeghoobi, Marzieh; Rahman, Noorsaadah Abd.
Monatshefte fur Chemie, 2012 , vol. 143, # 5 p. 797 - 800
反应条件
hydrogenchloride in water 12 h; Reflux;
参考文献
Dhiman, Rajni; Sharma, Sahil; Singh, Gagandip; Nepali, Kunal; Singh Bedi, Preet Mohinder
Archiv der Pharmazie, 2013 , vol. 346, # 1 p. 7 - 16
反应条件
1: aq. sodium hydroxide / ethanol / 40 h / 20 °C 2: phosphoric acid / acetic acid / 0.42 h / 90 °C View Scheme
参考文献
Tetrahedron, , vol. 53, # 39 p. 13397 - 13418
反应条件
1: 89 percent / p-toluenesulfonic acid / benzene / 48 h / 20 °C 2: aq. sodium hydroxide / ethanol / 40 h / 20 °C 3: phosphoric acid / acetic acid / 0.42 h / 90 °C View Scheme
参考文献
Tetrahedron, , vol. 53, # 39 p. 13397 - 13418
反应条件
1: 34 percent / dioxane / 8 h / Heating 2: 65 percent / AcOH, 90percent orthophosphoric acid / 0.25 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 55, # 6 p. 1757 - 1761
反应条件
1: sodium hydroxide / methanol; water / 6 h / 20 °C 2: hydrogenchloride / water / 12 h / |Reflux View Scheme
参考文献
Archiv der Pharmazie, , vol. 346, # 1 p. 7 - 16
反应条件
trimethylsilylazide; trifluoroacetic acid 120 h; Ambient temperature;
参考文献
Synthetic Communications, , vol. 23, # 7 p. 895 - 902
