4-(1-氧代-3-苯基烯丙基)吗啉合成路线 （共 4 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=-78°C; 12 h; Inert atmosphere;
参考文献
Synthesis, , # 15 art. no. Z09909SS, p. 2634 - 2645
反应条件
1: 79 percent / CrCl2 / tetrahydrofuran / 18 h / Heating
2: 89 percent / tetrahydrofuran / -78 - 20 °C
View Scheme
参考文献
Concellon, Jose M.; Rodriguez-Solla, Humberto; Mejica, Carmen; Blanco, Elena G.
Organic Letters, 2007 , vol. 9, # 16 p. 2981 - 2984
反应条件
1: n-butyllithium With cerium(III) chloride in tetrahydrofuran
T=-78°C; 2 h;
2: (E)-1-morpholin-4-yl-3-phenylprop-2-en-1-one in tetrahydrofuran
T=-78°C; 1.5 h; Further stages.;
参考文献
Badioli, Michele; Ballini, Roberto; Bartolacci, Massimo; Bosica, Giovanna; Torregiani, Elisabetta; Marcantoni, Enrico
The Journal of organic chemistry, 2002 , vol. 67, # 25 p. 8938 - 8942
反应条件
1: chloro(phenylmethyl)-magnesium With cerium(III) chloride in tetrahydrofuran
T=-78°C; 2 h;
2: (E)-1-morpholin-4-yl-3-phenylprop-2-en-1-one in tetrahydrofuran
T=-78°C; 1.5 h; Further stages.;
参考文献
Badioli, Michele; Ballini, Roberto; Bartolacci, Massimo; Bosica, Giovanna; Torregiani, Elisabetta; Marcantoni, Enrico
The Journal of organic chemistry, 2002 , vol. 67, # 25 p. 8938 - 8942
