3-(3-硝基苯基)丙酸合成路线 （共 14 条）
反应条件
hydroxylammonium sulfate; hydroxylamine-o-sulphonic acid in water T=10°C; 6 h; pH=7.6;
参考文献
Weichert; Longino; Bakan; Spigarelli; Chou -; Schwendner; Counsell
Journal of Medicinal Chemistry, 1995 , vol. 38, # 4 p. 636 - 646
反应条件
1: With water; sodium hydroxide in ethanol Reflux; 2: With hydrogenchloride in water
参考文献
Laboratorios Almirall, S.A.
Patent: EP2096105 A1, 2009 ;
Location in patent: Page/Page column 31 ;
反应条件
[Rh(OH)(cycloocta-1,5-diene)]2; water T=75°C; Miyaura-Hayashi reaction; 16 h; Inert atmosphere;
参考文献
Vautravers, Nicolas R.; Breit, Bernhard
Synlett, 2011 , # 17 p. 2517 - 2520
反应条件
triethylammonium formate T=95 - 100°C; 2 h;
参考文献
Nagel, Ulrike; Radau, Gregor; Link, Andreas
Archiv der Pharmazie, 2011 , vol. 344, # 12 p. 840 - 842
反应条件
(ethylenedinitrilo)tetraacetic acid disodium salt; thiamine diphosphate; anhydrous trisodium citrate; magnesium chloride in water; acetonitrile T=20°C; pH 6.0, brewers' yeast pyruvate decarboxylase (PDC, EC 4.1.1.1), also in the presence of pyruvamide; Rate constant;
参考文献
Journal of the American Chemical Society, , vol. 114, # 26 p. 10110 - 10112
反应条件
nitric acid in dichloromethane 24 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 63, # 4 p. 952 - 958
反应条件
1: alcohol / Verseifung des Diaethylesters mit Kalilauge 2: 180 °C View Scheme
参考文献
Journal of the Chemical Society, , p. 1674
反应条件
ethanol; nitric acid Behandeln nach Zugabe von Aether mit alkoh. Aethylnitrit, Erwaermen der Diazoniumverbindung mit Alkohol und Verseifen des entstandenen Esters durch Kochen mit konz. Salzsaeure;
参考文献
Chemische Berichte, , vol. 15, p. 846
参考文献
Journal of the Chemical Society, , p. 1674
反应条件
1: With sodium azide; sulfuric acid in chloroform T=50°C; 4 h; 2: With potassium carbonate in chloroform Product distribution / selectivity;
参考文献
Laboratorios Almirall, S.A.
Patent: EP2096105 A1, 2009 ;
Location in patent: Page/Page column 31 ;
