1-甲基-beta-咔啉-3-羧酸甲酯合成路线 （共 15 条）
反应条件
1: 88.5 percent / thionyl chloride / 16 h / 20 °C
2: 65 percent / KMnO4 / dimethylformamide / 14 h / 20 °C
View Scheme
参考文献
Zhao, Ming; Bi, Lanrong; Wang, Wei; Wang, Chao; Baudy-Floc'h, Michele; Ju, Jingfang; Peng, Shiqi
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 20 p. 6998 - 7010
反应条件
1: 31 percent / sulfuric acid; ammonia / H2O / 6 h / 20 °C / pH 6 - 7
2: 65 percent / KMnO4 / dimethylformamide / 14 h / 20 °C
View Scheme
参考文献
Zhao, Ming; Bi, Lanrong; Wang, Wei; Wang, Chao; Baudy-Floc'h, Michele; Ju, Jingfang; Peng, Shiqi
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 20 p. 6998 - 7010
反应条件
nitrosyl chloride in chloroform
T=0°C; 0.166667 h;
参考文献
Salvi; Choughuley
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 10 p. 986 - 988
反应条件
trichloroisocyanuric acid; toluene-4-sulfonic acid; triethylamine
1.) toluene, reflux, 2 h; 2.) DMF, 0 degC, 2 h; Yield given. Multistep reaction;
参考文献
Haffer, Gregor; Nickisch, Klaus; Tilstam, Ulf
Heterocycles, 1998 , vol. 48, # 5 p. 993 - 998
参考文献
Nakatsuka, Shin-ichi; Feng, Bai-nian; Goto, Toshio; Kihara, Kiyoshi
Tetrahedron Letters, 1986 , vol. 27, # 29 p. 3399 - 3402
