N-BOC-4-氧代-L-脯氨酸叔丁酯合成路线 （共 6 条）
反应条件
1-methyl-pyrrolidin-2-one; tetrapropylammonium perruthennate; 4 A molecular sieve in dichloromethane T=20°C; 3 h;
参考文献
Tamaki; Han; Hruby
Journal of Organic Chemistry, 2001 , vol. 66, # 10 p. 3593 - 3596
反应条件
tetrapropylammonium perruthennate; silica gel in hexane; dichloromethane; ethyl acetate
参考文献
Merck and Co., Inc.
Patent: US5821261 A1, 1998 ;
反应条件
4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane 3 h; Ambient temperature;
参考文献
Barraclough, Paul; Hudhomme, Pietrick; Spray, Caroline A.; Young, Douglas W.
Tetrahedron, 1995 , vol. 51, # 14 p. 4195 - 4212
反应条件
1: Na2CO3 2: 86 percent / tetrahydrofuran / 55 - 60 °C 3: 90 percent / TPAP; NMP; 4 Angstroem molecular sieves / CH2Cl2 / 3 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 10 p. 3593 - 3596
反应条件
1: 86 percent / tetrahydrofuran / 55 - 60 °C 2: 90 percent / TPAP; NMP; 4 Angstroem molecular sieves / CH2Cl2 / 3 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 10 p. 3593 - 3596
反应条件
1: Na2CO3 2: 86 percent / tetrahydrofuran / 55 - 60 °C 3: 90 percent / TPAP; NMP; 4 Angstroem molecular sieves / CH2Cl2 / 3 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 10 p. 3593 - 3596
