3-(4-硝基苯基)丙酸合成路线 （共 25 条）
反应条件
nitric acid in water; acetic acid T=20°C; 4 h; Cooling with ice;
参考文献
Pinto, Orlando; Sardinha, Joao; Vaz, Pedro D.; Piedade, Fatima; Calhorda, Maria J.; Abramovitch, Rudolph; Nazareth, Nair; Pinto, Madalena; Nascimento, Maria S. J.; Rauter, Amelia P.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 9 p. 3175 - 3187
反应条件
2,2-Dimethyl-[1,3]dioxane-4,6-dione in N,N-dimethyl-formamide T=20 - 50°C; 21 h;
参考文献
TEVA PHARMACEUTICAL INDUSTRIES, LTD.; TEVA PHARMACEUTICALS USA, INC.
Patent: WO2006/20070 A2, 2006 ;
Location in patent: Page/Page column 50 ;
反应条件
1: With potassium carbonate; Pd-Tedicyp catalyst in N,N-dimethyl-formamide T=110°C; Heck reaction; 20 h; 2: With sodium hydroxide; water in N,N-dimethyl-formamide T=50 - 80°C;
参考文献
Lemhadri, Mhamed; Doucet, Henri; Santelli, Maurice
Tetrahedron, 2004 , vol. 60, # 50 p. 11533 - 11540
反应条件
triethylammonium formate T=95 - 100°C; 72 h;
参考文献
Toth; Kover
Synthetic Communications, 1995 , vol. 25, # 19 p. 3067 - 3074
反应条件
methanol; formic acid; water; silica gel; palladium dichloride 0.666667 h; Irradiationmicrowave;
参考文献
Sharma, Anuj; Kumar, Vinod; Sinha, Arun K.
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 3 p. 354 - 360
参考文献
Chemische Berichte, , vol. 12, p. 600
Zeitschrift fuer Chemie, , p. 193
Justus Liebigs Annalen der Chemie, , vol. 163, p. 126
反应条件
nitric acid in dichloromethane 24 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 63, # 4 p. 952 - 958
参考文献
Journal of the Chemical Society, , p. 2706,2710
反应条件
1: amalgamated sodium; aqueous NaOH 2: H2SO4; aqueous HNO3 View Scheme
参考文献
Bl. Inst. Insect. Control KyotoChem.Abstr., , vol. 19, p. 47,49
Bl. Inst. Insect. Control KyotoChem.Abstr., , p. 14094
反应条件
T=150 - 160°C; im geschlossenen Rohr;
参考文献
Chemische Berichte, , vol. 37, p. 1992
