3-(4-硝基苯基)丙酸合成路线 (共 25 条)
参考文献
Chemische Berichte, , vol. 12, p. 600
Zeitschrift fuer Chemie, , p. 193
Justus Liebigs Annalen der Chemie, , vol. 163, p. 126
反应条件
bei der elektrolytischen Reduktion mit Platinelektroden;
参考文献
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 140, p. 1248
反应条件
1: BH3-Me2S complex / tetrahydrofuran / 1 h / 20 °C 2: pyridine / 3 h / 20 °C 3: NaI / acetone / 18 h / 20 °C View Scheme
参考文献
Pinto, Orlando; Sardinha, Joao; Vaz, Pedro D.; Piedade, Fatima; Calhorda, Maria J.; Abramovitch, Rudolph; Nazareth, Nair; Pinto, Madalena; Nascimento, Maria S. J.; Rauter, Amelia P.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 9 p. 3175 - 3187
参考文献
McKeown, Stephen C.; Corbett, David F.; Goetz, Aaron S.; Littleton, Thomas R.; Bigham, Eric; Briscoe, Celia P.; Peat, Andrew J.; Watson, Steve P; Hickey, Deirdre M.B.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 6 p. 1584 - 1589
反应条件
1: oxalyl chloride; DMF / toluene / 2 h / 20 °C 2: 4.3 g / triethylamine / CH2Cl2 / 18 h / Heating 3: 78.6 percent / SnCl2*2H2O / ethanol / 1.5 h / Heating View Scheme
参考文献
Tomlinson, Ian D.; Mason, John; Burton, Jon N.; Blakely, Randy; Rosenthal, Sandra J.
Tetrahedron, 2003 , vol. 59, # 40 p. 8035 - 8047
反应条件
toluene-4-sulfonic acid in pyridine 17 h; Heating;
参考文献
Coutts, Ian G. C.; Culbert, Nicholas J.; Edwards, Mark; Hadfield, John A.; Musto, Donald R.; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1829 - 1836
反应条件
1: H2 / Pd View Scheme
参考文献
CHIESI FARMACEUTICI S.P.A.; ARMANI, Elisabetta; AMARI, Gabriele; CAPALDI, Carmelida; ESPOSITO, Oriana; PERETTO, Ilaria
Patent: WO2013/45280 A1, 2013 ;
反应条件
formic acid; triethylamine; palladium on activated carbon T=90 - 95°C; 3.5 h; Heating / reflux;
参考文献
WO2006/20070 A2, ;
Page/Page column 50 ;
参考文献
Chemische Berichte, , vol. 15, p. 846
参考文献
Zeitschrift fuer Chemie, , p. 193