4-溴-2,3-二氢-1H-茚-1-醇合成路线 （共 16 条）
反应条件
4-(N,N-dimethlyamino)pyridine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid in toluene T=120°C; 4 h; sealed tube;
参考文献
Kirchberg, Sylvia; Froehlich, Roland; Studer, Armido
Angewandte Chemie - International Edition, 2010 , vol. 49, # 38 p. 6877 - 6880
反应条件
1: 92 percent / p-toluenesulfonic acid*H2O / benzene / 1 h / Heating
2: 96 percent / NiCl2<dppp>2 / diethyl ether / 22 h / Heating
View Scheme
参考文献
Adamczyk, Maciej; Watt, David S.; Netzel, Daniel A.
Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4226 - 4237
反应条件
tris-imidazolium-stabilized palladium; potassium carbonate in water; toluene
T=90°C; Suzuki coupling; 22 h;
参考文献
Planellas, Marc; Pleixats, Roser; Shafir, Alexandr
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 4 p. 651 - 662
反应条件
1: 92 percent / p-toluenesulfonic acid*H2O / benzene / 1 h / Heating
2: 98 percent / NiCl2<dppp>2 / diethyl ether / Heating
3: 97 percent / H2 / PtO2 / tetrahydrofuran / 1034.3 Torr
View Scheme
参考文献
Adamczyk, Maciej; Watt, David S.; Netzel, Daniel A.
Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4226 - 4237
反应条件
1: 92 percent / p-toluenesulfonic acid*H2O / benzene / 1 h / Heating
2: 96 percent / NiCl2<dppp>2 / diethyl ether / 22 h / Heating
3: 98 percent / H2 / PtO2 / tetrahydrofuran / 1034.3 Torr
View Scheme
参考文献
Adamczyk, Maciej; Watt, David S.; Netzel, Daniel A.
Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4226 - 4237
反应条件
1: 92 percent / p-toluenesulfonic acid*H2O / benzene / 1 h / Heating
2: 99 percent / NiCl2<dppp>2 / diethyl ether / Heating
3: 97 percent / H2 / PtO2 / tetrahydrofuran / 1034.3 Torr
View Scheme
参考文献
Adamczyk, Maciej; Watt, David S.; Netzel, Daniel A.
Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4226 - 4237
