2-N-Boc-1,2,3,4-四氢异喹啉-1-羧酸合成路线 (共 3 条)
反应条件
sodium hydroxide in tert-butyl alcohol
参考文献
Ho, Bin; Michael Crider; Stables, James P
European Journal of Medicinal Chemistry, 2001 , vol. 36, # 3 p. 265 - 286
反应条件
1: 59 percent / H2 / PtO2 / acetic acid / 24 h / 3102.89 Torr 2: 84 percent / aq. NaOH / 2-methyl-propan-2-ol View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 36, # 3 p. 265 - 286
反应条件
1: With cesium fluoride in N,N-dimethyl-formamide T=100°C; P=7500.75 Torr; 3 h; Autoclave; 2: With hydrogenchloride in diethyl ether; water; N,N-dimethyl-formamide T=0°C; pH=2; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 77, # 5 p. 2159 - 2168