1.1: n-BuLi; t-BuOK / tetrahydrofuran; hexane / 0.76 h / -80 °C 1.2: 91 percent / tetrahydrofuran; hexane / 0.08 h / -80 °C 2.1: aq. NaIO4 / methanol / 4 h / 20 °C 3.1: benzene / 18 h / Heating 4.1: 0.06 g / aq. H2O2; KF; KHCO3 / methanol; tetrahydrofuran / 12 h / 20 °C View Scheme

1.1: n-BuLi; t-BuOK / tetrahydrofuran; hexane / 0.76 h / -80 °C 1.2: 91 percent / tetrahydrofuran; hexane / 0.08 h / -80 °C 2.1: aq. NaIO4 / methanol / 4 h / 20 °C 3.1: benzene / 18 h / Heating 4.1: 0.06 g / aq. H2O2; KF; KHCO3 / methanol; tetrahydrofuran / 12 h / 20 °C View Scheme

1.1: n-BuLi; t-BuOK / tetrahydrofuran; hexane / 0.75 h / -80 °C 1.2: 90 percent / tetrahydrofuran; hexane / 0.08 h / -80 °C 2.1: 100 percent / aq. H2O2; V2O5 / 2-methyl-propan-2-ol / 0.17 h / 20 °C 3.1: 85 percent / aq. H2O2; KF; KHCO3 / tetrahydrofuran; methanol / 12 h / 20 °C View Scheme

1.1: n-BuLi; t-BuOK / tetrahydrofuran; hexane / 0.75 h / -80 °C 1.2: tetrahydrofuran; hexane / 0.08 h / -80 °C 1.3: 65 percent / aq. H2SO4 / 1 h / 20 °C 2.1: m-CPBA / CH2Cl2 / 2 h / 20 °C 3.1: 70 percent / aq. H2O2; KF; KHCO3 / methanol; tetrahydrofuran / 12 h / 20 °C View Scheme