(2S)-2-氨基-6-庚烯酸合成路线 (共 2 条)
反应条件
1: With sodium hydroxide in acetonitrile
T=20°C; Alkylation; 3 h;
2: With hydrogenchloride; water in methanol
Hydrolysis; 1 h; Heating; Further stages.;
参考文献
Collet, Sylvain; Carreaux, Francois; Boucher, Jean-Luc; Pethe, Stephanie; Lepoivre, Michel; Danion-Bougot, Renee; Danion, Daniel
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 2 p. 177 - 182
反应条件
potassium hydroxide; potassium phosphate buffer; porcine kidney acylase I
T=40°C; relative initial rate of hydrolysis, also with Aspergillus acylase I as a catalyst; with or without CoCl2;
参考文献
Chenault, H. Keith; Dahmer, Juergen; Whitesides, George M.
Journal of the American Chemical Society, 1989 , vol. 111, # 16 p. 6354 - 6364