2-(溴甲基)-5-(邻苯二甲酰亚氨基甲基)噻吩合成路线 （共 2 条）
反应条件
1: 2,5-dimethyl-thiophene With N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane 0.333333 h; Heating / reflux; 2: potassium phtalimide With tetrabutylammomium bromide in acetonitrile T=20°C; 64 h;
参考文献
AstraZeneca AB
Patent: US6346625 B1, 2002 ;
Location in patent: Page column 27 ;
US 6346625 B1
反应条件
triphenylphosphine in dichloromethane
参考文献
Glaxo Wellcome Inc.
Patent: US5874472 A1, 1999 ;
