hydrogen; palladium 10 on activated carbon in methanol P=1551.49 Torr; 0.5 h;

trifluoroacetic acid in dichloromethane T=20°C; 2 h;

1: With trifluoroacetic anhydride in dichloromethane T=20°C; 1.5 h; 2: With sodium hydroxide in dichloromethane; water

1: sulfuric acid / 2 h / Reflux 2: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 1 h / 20 °C 3: hydrogen / platinum(IV) oxide / ethanol / 1 h / 20 °C / 2585.81 Torr / Inert atmosphere 4: trifluoroacetic acid / dichloromethane / 2 h / 20 °C View Scheme

1: hydrogen / platinum(IV) oxide / ethanol / 1 h / 20 °C / 2585.81 Torr / Inert atmosphere 2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C View Scheme