acetylesterase from orange peel;

Amberlite IRA-400 OH form 40 h; Ambient temperature;

2: 66 percent / 0.05M NaOMe / methanol / 9 h / Ambient temperature 3: 1.) thiourea, 2.) KOAc / 1.) MeOH, RT, 5d, 2.) AcOH, 140 deg C, 19h 4: 24 percent / 2.8percent HCl / H2O / 27 h / Heating View Scheme

sodium hydroxide; tetra-(n-butyl)ammonium iodide in tetrahydrofuran T=20°C; 3 h;

1: 87 percent / aq. acetic acid / 24 h / 20 °C 2: 1) Ph3P, imidazole, iodine, 2) aq. NaOH / 1) toluene, 80 deg C, 3 h, 2) methanol, RT, 30 min 3: 1) 2-methyl-2-butene, borane-THF, 2) aq. NaOH, H2O2 / 1) THF, 0 deg C, 1 h, 2) RT View Scheme

1: 87 percent / aq. acetic acid / 24 h / 20 °C 2: 1) Ph3P, imidazole, iodine, 2) aq. NaOH / 1) toluene, 80 deg C, 3 h, 2) methanol, RT, 30 min View Scheme