2,6-二甲氧基吡啶-3-羧酸合成路线 （共 5 条）
反应条件
potassium tert-butylate T=60°C; 1 h; Microwave irradiation; regioselective reaction;
参考文献
Synlett, , # 2 art. no. S05610ST, p. 203 - 206
反应条件
Pd(OTf)2; silver carbonate in dimethyl sulfoxide; N,N-dimethyl-formamide T=100°C;
参考文献
Synlett, , # 14 art. no. G18110ST, p. 2083 - 2086
反应条件
1: With palladium (II) trifluoroacetate; 6-mbipy in water
T=130°C; 1 h; Microwave irradiation;
2: With formic acid in water
T=100°C; 1 h;
参考文献
Lindh, Jonas; Sjoeberg, Per J. R.; Larhed, Mats
Angewandte Chemie - International Edition, 2010 , vol. 49, # 42 p. 7733 - 7737
反应条件
thionyl chloride; urea in toluene
参考文献
Hormann, Robert Eugene; Potter, David W.; Chortyk, Orestes; Tice, Colin M.; Carlson, Glenn Richard; Meyer, Andrew; Opie, Thomas R.
Patent: US2006/20146 A1, 2006 ;
Location in patent: Page/Page column 45 ;
反应条件
sulfuric acid
48 h; Heating / reflux;
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1460062 A1, 2004 ;
Location in patent: Page 63 ;
