5-(3-氯苯基)-1,3,4-噁二唑-2-胺合成路线 （共 4 条）
反应条件
Oxonereg;; iodine; sodium hydroxide in water; isopropyl alcohol T=0 - 20°C; 0.5 h;
参考文献
Shinde, Vikas N.; Ugarkar, Bheemarao G.; Ghorpade, Sandeep R.
Journal of Chemical Research, 2013 , vol. 37, # 1 p. 53 - 54
反应条件
1: (i) N2H4*H2O, (ii) /BRN= 3595135/, aq. HCl 2: Pb3O4 / ethanol / Heating View Scheme
参考文献
Journal of medicinal chemistry, , vol. 9, # 4 p. 478 - 483
反应条件
1: sodium acetate / water / 20 °C 2: bromine; sodium acetate / acetic acid / 0.5 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 19 p. 5735 - 5738
反应条件
1: tetrahydrofuran / 24 h / 0 - 20 °C / |Inert atmosphere 2: potassium iodide; sodium hydroxide; 1,3-dibromo-5,5-dimethyl-hydantoin / isopropyl alcohol; water; acetonitrile / 1 h / 0 - 4 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 17 p. 6761 - 6774
