(±)-2-氯-1-苯基乙醇合成路线 （共 94 条）
反应条件
chiral 2-(3',5'-di-t-butylPh)-2-phosphabicyclo[3.3.0]octane in n-heptane T=-20°C; 1.3 h; Title compound not separated from byproducts;
参考文献
Vedejs, Edwin; Daugulis, Olafs
Journal of the American Chemical Society, 2003 , vol. 125, # 14 p. 4166 - 4173
反应条件
in helium T=130°C; P=750.075 Torr; Chirasil-DEX CB; Resolution of racemateGas phase; Product distribution / selectivity;
参考文献
Mutti, Francesco G.; Orthaber, Andreas; Schrittwieser, Joerg H.; Vries, Johannes G. De; Pietschnig, Rudolf; Kroutil, Wolfgang
Chemical Communications, 2010 , vol. 46, # 42 p. 8046 - 8048
反应条件
Pseudomonas cepacia lipase immobilized on toyonite; potassium tert-butylate; sodium carbonate; [2,3,4,5-Ph4(η5-C4CNH(i-Pr))]Ru(CO)2Cl in toluene T=25°C; 168 h;
参考文献
Choi, Jun Ho; Choi, Yoon Kyung; Kim, Yu Hwan; Park, Eun Sil; Kim, Eun Jung; Kim, Mahn-Joo; Park, Jaiwook
Journal of Organic Chemistry, 2004 , vol. 69, # 6 p. 1972 - 1977
反应条件
Novozyme[435] in tetrahydrofuran; dimethyl sulfoxide T=30°C; 7 h;
参考文献
Zagozda, Marcin; Plenkiewicz, Jan
Tetrahedron Asymmetry, 2007 , vol. 18, # 12 p. 1457 - 1464
反应条件
Lipase PS in di-isopropyl ether T=30°C; Esterification; 96 h; Enzymatic reaction; Title compound not separated from byproducts.;
参考文献
Kita, Yasuyuki; Takebe, Yasushi; Murata, Kenji; Naka, Tadaatsu; Akai, Shuji
Journal of Organic Chemistry, 2000 , vol. 65, # 1 p. 83 - 88
反应条件
lipase Amano PS enzyme in di-isopropyl ether T=30°C; 96 h; Yield given. Yields of byproduct given;
参考文献
Kita, Yasuyuki; Takebe, Yasushi; Murata, Kenji; Naka, Tadaatsu; Akai, Shuji
Tetrahedron Letters, 1996 , vol. 37, # 41 p. 7369 - 7372
反应条件
halohydrin dehalogenase from Agrobacterium radiobacter AD1; Tris-SO4 buffer in water T=30°C; Dehydrochlorination; pH=7.5; Title compound not separated from byproducts;
参考文献
Lutje Spelberg, Jeffrey H.; Van Hylckama Vlieg, Johan E. T.; Bosma, Tjibbe; Kellogg, Richard M.; Janssen, Dick B.
Tetrahedron Asymmetry, 1999 , vol. 10, # 15 p. 2863 - 2870
反应条件
1: 1-hydroxy-2-chloroethylbenzene With Pseudomonas aeruginosa lipase in isopropyl alcohol T=30°C; 0.5 h; Enzymatic reaction; 2: vinyl acetate in isopropyl alcohol T=30°C; 1 h; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron, , vol. 65, # 46 p. 9583 - 9591
参考文献
Hiratake, Jun; Inagaki, Minoru; Nishioka, Takaaki; Oda, Jun'ichi
Journal of Organic Chemistry, 1988 , vol. 53, # 26 p. 6130 - 6133
Title/Abstract Full Text View citing articles Show Details
Ruble; Latham; Fu
Journal of the American Chemical Society, 1997 , vol. 119, # 6 p. 1492 - 1493
反应条件
Pseudomonas sp. lipase in toluene T=60°C; 5 h; Enzymatic reaction; Product distribution; Further Variations:Reagents;
参考文献
Pamies, Oscar; Baeckvall, Jan-E.
Journal of Organic Chemistry, 2002 , vol. 67, # 25 p. 9006 - 9010
