1: diethylamine; N-(2,6-dimethylphenyl)-2-chloroacetamide With sodium carbonate in water T=30 - 90°C; 12 h; 2: benzyl chloride in water T=70 - 90°C; 20 - 24 h; Product distribution / selectivity;
参考文献
DISHMAN PHARMACEUTICALS AND CHEMICALS LTD.; PLUIM, Henk
Patent: WO2006/62406 A2, 2006 ;
Location in patent: Page/Page column 7 ;