5-(4-吡啶基)-1,2-恶唑-3(2H)-酮合成路线 （共 1 条）
反应条件
1: 90 percent / HBr, Br2 / acetone / 1.) 20 deg C, 30 min, 2.) 60 deg C, 3 h 2: 72 percent / NaOH, NH2OH*HCl / methanol / 1.) 0 deg C, 1 h, 2.) reflux, 2 h View Scheme
参考文献
Froelund, Bente; Kristiansen, Uffe; Brehm, Lotte; Hansen, Annette B.; Krogsgaard-Larsen, Povl; Falch, Erik
Journal of Medicinal Chemistry, 1995 , vol. 38, # 17 p. 3287 - 3296
