1-甲基-1H-吲哚-7-羧酸合成路线 （共 7 条）
反应条件
sodium hydroxide in methanol; water 8 h; Heating;
参考文献
Heterocycles, , vol. 67, # 2 p. 643 - 653
反应条件
quinoline; copper(II) oxide T=180°C; Decarboxylation; 1 h;
参考文献
Kitano, Masafumi; Kojima, Atsuyuki; Nakano, Kazuhiro; Miyagishi, Akira; Noguchi, Tsuyoshi; Ohashi, Naohito
Chemical and Pharmaceutical Bulletin, 1999 , vol. 47, # 11 p. 1538 - 1548
参考文献
US6372764 B1, ;
US 6372764 B1
反应条件
sodium hydroxide in ethanol; water 8 h; Heating;
参考文献
Heterocycles, , vol. 67, # 2 p. 643 - 653
反应条件
1.1: NaH / dimethylformamide / 1 h / 0 °C 1.2: dimethylformamide / 2.5 h / 0 - 20 °C 2.1: NaOH / methanol; H2O / 8 h / Heating View Scheme
参考文献
Heterocycles, , vol. 67, # 2 p. 643 - 653
反应条件
1.1: NaH / dimethylformamide / 1 h / 20 °C 1.2: 98.5 percent / dimethylformamide / 5 h / 20 °C 2.1: 98.6 percent / 2 N aq. NaOH / ethanol / 3 h / Heating 3.1: 49 percent / CuO; quionoline / 1 h / 180 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 47, # 11 p. 1538 - 1548
反应条件
1: 98.6 percent / 2 N aq. NaOH / ethanol / 3 h / Heating 2: 49 percent / CuO; quionoline / 1 h / 180 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 47, # 11 p. 1538 - 1548
