5-氟-1H-吲哚-2-羧酸甲酯合成路线 （共 6 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; N-ethyl-N,N-diisopropylamine; triphenylphosphine in tetrahydrofuran T=110°C; P=7600.51 Torr; 20 h; Autoclave;
参考文献
Vieira, Tiago O.; Meaney, Laura A.; Shi, Yong-Ling; Alper, Howard
Organic Letters, 2008 , vol. 10, # 21 p. 4899 - 4901
反应条件
copper(I) oxide; caesium carbonate in 1-methyl-pyrrolidin-2-one T=100°C; 16 h; Inert atmosphereSealed tube;
参考文献
Zhu, Zhiqiang; Yuan, Jiangjun; Zhou, Yirong; Qin, Yang; Xu, Jingshi; Peng, Yiyuan
European Journal of Organic Chemistry, 2014 , vol. 2014, # 3 p. 511 - 514
反应条件
hydrogenchloride T=20°C;
参考文献
Journal of Medicinal Chemistry, , vol. 48, # 14 p. 4511 - 4525
反应条件
1: 54 percent / 1,8-diazabicyclo[5.4.0]undec-7-ene / CH2Cl2 / 2 h / 20 °C 2: 26 percent / K2CO3; L-proline / CuI / dioxane / 24 h / 100 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 46, # 51 p. 8877 - 8880
反应条件
1: sodium; methanol / -10 °C 2: toluene / 0.17 h / 200 °C / |Microwave irradiation View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 6 p. 1740 - 1742
反应条件
1: KOH / acetone / 0 - 20 °C
2: LiAlH4 / tetrahydrofuran / 0 - 20 °C
View Scheme
参考文献
Li, Chang-Feng; Liu, Hiu; Liao, Jie; Cao, Yi-Ju; Liu, Xiao-Peng; Xiao, Wen-Jing
Organic Letters, 2007 , vol. 9, # 10 p. 1847 - 1850
