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63148-62-9
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二甲基亚砜
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471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
16765-79-0
合成路线
(共 32 条)
16765-79-0
→
反应条件
127042-80-2
反应条件
1: 35 percent / conc. HNO3, gl. acetic acid / acetic acid / 8 h / Heating 2: 69 percent / H2 / Raney nickel / ethanol / 1838.8 Torr View Scheme
参考文献
Agarwal; Bhakuni; Gupta; Katiyar
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 11 p. 943 - 949
209169-30-2
→
反应条件
16765-79-0
反应条件
copper dichloride in N,N-dimethyl-formamide T=130°C; 1 h;
参考文献
Meesala, Ramu; Mordi, Mohd Nizam; Mansor, Sharif Mahsufi
Synlett, 2014 , vol. 25, # 1 art. no. ST-2013-D0848-L, p. 120 - 122
10022-79-4
→
反应条件
16765-79-0
反应条件
potassium permanganate in acetone T=20°C;
参考文献
Trieu, Tien Ha; Dong, Jing; Zhang, Qiang; Zheng, Bo; Meng, Tian-Zhuo; Lu, Xia; Shi, Xiao-Xin
European Journal of Organic Chemistry, 2013 , # 16 p. 3271 - 3277
17071-83-9
→
反应条件
16765-79-0
反应条件
oxygen; sodium hydroxide in water; dimethyl sulfoxide T=125°C; 4 h;
参考文献
Dong, Jing; Shi, Xiao-Xin; Yan, Jing-Jing; Xing, Jing; Zhang, Qiang; Xiao, Sen
European Journal of Organic Chemistry, 2010 , # 36 p. 6987 - 6992
50302-58-4
→
反应条件
16765-79-0
反应条件
(NH4)2S2O8; silver nitrate in water; acetonitrile T=80°C;
参考文献
Huang, Wenhua; Li, Jingyi; Ou, Lihua
Synthetic Communications, 2007 , vol. 37, # 13 p. 2137 - 2143
4753-09-7
→
反应条件
16765-79-0
反应条件
1: With trifluoromethylsulfonic anhydride; triphenyl-phosphine oxide in chlorobenzene T=20 - 130°C; 2: With manganese(IV) oxide in chlorobenzene T=130°C; 4 h;
参考文献
Wu, Mengde; Wang, Shaozhong
Synthesis, 2010 , # 4 art. no. F18709SS, p. 587 - 592
61-54-1
色胺
+
100-52-7
苯甲醛
→
反应条件
16765-79-0
反应条件
1: in dichloromethane 2: With montmorillonite K-10; palladium 10 on activated carbon in methanol; dichloromethane Pictet-Spengler cyclisation; 0.0833333 h; 3: T=130°C; 0.75 h; Microwave irradiation;
参考文献
Kulkarni, Aditya; Abid, Mohammed; Toeroek, Bela; Huang, Xudong
Tetrahedron Letters, 2009 , vol. 50, # 16 p. 1791 - 1794
3790-45-2
1-苯基-2,3,4,9-四氢-1H-beta-咔啉
→
反应条件
4894-26-2
4,9-二氢-3H-吡啶并(3,4-B)吲哚
+
16765-79-0
反应条件
tetrabutylammomium bromide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in acetonitrile T=20°C; 2 h;
参考文献
Panarese, Joseph D.; Waters, Stephen P.
Organic Letters, 2010 , vol. 12, # 18 p. 4086 - 4089
3790-45-2
1-苯基-2,3,4,9-四氢-1H-beta-咔啉
→
反应条件
16765-79-0
反应条件
C21H21ClIrNO2 in tetrahydrofuran; 2,2,2-trifluoroethanol 20 h; Inert atmosphere;
参考文献
Wu, Jianjun; Talwar, Dinesh; Johnston, Steven; Yan, Ming; Xiao, Jianliang
Angewandte Chemie - International Edition, 2013 , vol. 52, # 27 p. 6983 - 6987
Ross. Khim. Zh., 2013 , vol. 125, # 27 p. 7121 - 7125,5
82980-12-9
+
100-47-0
苯甲腈
→
反应条件
16765-79-0
反应条件
1: 3-ethenyl-1-phenylsulfonyl-1H-indole With lithium diisopropyl amide in tetrahydrofuran T=-78°C; 1 h; 2: benzonitrile in tetrahydrofuran T=-78 - -10°C; 3: With hydroxylamine hydrochloride; sodium acetate in 1,2-dichloro-benzene 8 h; Heating;
参考文献
Kusurkar, Radhika S.; Goswami, Shailesh K.
Tetrahedron, 2004 , vol. 60, # 25 p. 5315 - 5318
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