8-(2-苯基乙基)-1,4-二氧杂-8-氮杂螺[4.5]癸烷合成路线 （共 3 条）
反应条件
trifluorormethanesulfonic acid; 1,5-bis-(diphenylphosphino)-pentane; [Ru(η4-COD)(η3-methylallyl)2] in 1,4-dioxane T=100°C; 24 h;
参考文献
YALE UNIVERSITY
Patent: WO2005/77885 A1, 2005 ;
Location in patent: Page/Page column 20-21; 30 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide T=70°C;
参考文献
Dutta; Xu; Reith
Journal of Medicinal Chemistry, 1996 , vol. 39, # 3 p. 749 - 756
反应条件
hydrogenchloride in benzene 24 h; Heating;
参考文献
Dutta; Xu; Reith
Journal of Medicinal Chemistry, 1996 , vol. 39, # 3 p. 749 - 756
