3,3-二乙氧基-1-丙醇合成路线 （共 13 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=10 - 20°C; 1 h; 2: With water in tetrahydrofuran 2 h; Product distribution / selectivity;
参考文献
NOF CORPORATION
Patent: US2012/277477 A1, 2012 ;
Location in patent: Page/Page column 5 ;
反应条件
ammonia; sodium in tetrahydrofuran T=-78°C;
参考文献
Uenishi; Motoyama; Takahashi
Tetrahedron Asymmetry, 1994 , vol. 5, # 1 p. 101 - 110
反应条件
ammonium nitrate in ethanol
参考文献
Journal of Medicinal Chemistry, , vol. 18, p. 376 - 383
反应条件
sodium hydroxide; water T=115°C;
参考文献
Chemische Berichte, , vol. 33, p. 2763
反应条件
sodium hydroxide; dimethylsulfide borane complex; dihydrogen peroxide 1.) THF, 0 deg C up to rt, 2.) 40 deg C, 16 h; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 48, # 10 p. 1895 - 1910
反应条件
sodium hydroxide; dihydrogen peroxide; bis-(1,2-dimethylpropyl)borane 1)THF, 0 deg C, 7 h; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 46, # 20 p. 3978 - 3988
反应条件
NaH in N-methyl-acetamide; water
参考文献
Polaroid Corporation
Patent: US4636568 A1, 1987 ;
反应条件
dipyridinium dichromate; 3 A molecular sieve in dichloromethane Ambient temperature;
参考文献
Benechie, Michel; Delpech, Bernard; Khuong-Huu, Qui; Khuong-Huu, Francoise
Tetrahedron, 1992 , vol. 48, # 10 p. 1895 - 1910
反应条件
1: 1.) DMSO, oxalyl chloride, 2.) Et3N / 1.) CH2Cl2, -78 deg C, 20 min, 2.) CH2Cl2, 0 deg C, 30 min
2: 1.) NaH / 1.) THF, RT, 2.) THF, RT, 30 min
3: 95 percent / DIBALH / CH2Cl2; hexane / 0.17 h / -78 °C
View Scheme
参考文献
Uenishi; Motoyama; Takahashi
Tetrahedron Asymmetry, 1994 , vol. 5, # 1 p. 101 - 110
反应条件
pyridinium p-toluenesulfonate in dichloromethane
24 h; Ambient temperature;
参考文献
Barbier, Denis; Salvi, Jean-Paul; Walchshofer, Nadia; Paris, Joelle
Organic Preparations and Procedures International, 1994 , vol. 26, # 1 p. 121 - 122
