3-溴-4-硝基吡啶-N-氧化物合成路线 （共 37 条）
反应条件
Re(O)(Ph3P)2Cl3; triphenylphosphine in dichloromethane T=20 - 40°C;
参考文献
Yao, Jiangchao; Blake, Paul R.; Yang, Ji
Heterocycles, 2005 , vol. 65, # 9 p. 2071 - 2081
反应条件
1: 85 percent / dioxane / 0.5 h / 50 °C 2: 66 percent / iron, conc. hydrochloric acid / H2O; ethanol / 3 h / Heating View Scheme
参考文献
Yutilov, Yu. M.; Shcherbina, L. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 5 p. 529 - 535
Khimiya Geterotsiklicheskikh Soedinenii, 1987 , vol. 23, # 5 p. 639 - 645
反应条件
potassium tert-butylate in tert-butyl alcohol T=20°C; 12 h;
参考文献
YUHAN CORPORATION
Patent: WO2007/1139 A1, 2007 ;
Location in patent: Page/Page column 14 ;
反应条件
iron in acetic acid T=80°C; 1.5 h;
参考文献
Tee, Oswald S.; Paventi, Martino
Canadian Journal of Chemistry, 1983 , vol. 61, p. 2556 - 2562
反应条件
potassium carbonate in toluene 10 h; Heating;
参考文献
Julemont, Fabien; De Leval, Xavier; Michaux, Catherine; Renard, Jean-Francois; Winum, Jean-Yves; Montero, Jean-Louis; Damas, Jacques; Dogne, Jean-Michel; Pirotte, Bernard
Journal of Medicinal Chemistry, 2004 , vol. 47, # 27 p. 6749 - 6759
反应条件
1: 75 percent / 20percent aq. TiCl3 / acetic acid / 25 h / Ambient temperature View Scheme
参考文献
Okuda; Robison
Journal of Organic Chemistry, 1959 , vol. 24, p. 1008,1010
反应条件
1: 75 percent / 20percent aq. TiCl3 / acetic acid / 25 h / Ambient temperature 3: 93 percent / Pd(PPh3)2Cl2, Et4NCl / acetonitrile / 2.5 h / Heating 4: 90 percent / conc. HCl / methanol / 2 h / Heating View Scheme
参考文献
Sakamoto, Takao; Satoh, Chisato; Kondo, Yoshinori; Yamanaka, Hiroshi
Heterocycles, 1992 , vol. 34, # 12 p. 2379 - 2384
反应条件
1: 54 percent / Heating
2: 90 percent / Fe; aq. AcOH / Heating
3: 61 percent / potassium carbonate / acetonitrile / 12 h
View Scheme
参考文献
Cignarella; Vianello; Berti; Rossoni
European Journal of Medicinal Chemistry, 1996 , vol. 31, # 5 p. 359 - 364
反应条件
1: 2-chlorophenol With sodium hydroxide
2: 3-bromo-4-nitro-pyridine-1-oxide in acetonitrile
12 h; Heating;
参考文献
Julemont, Fabien; De Leval, Xavier; Michaux, Catherine; Renard, Jean-Francois; Winum, Jean-Yves; Montero, Jean-Louis; Damas, Jacques; Dogne, Jean-Michel; Pirotte, Bernard
Journal of Medicinal Chemistry, 2004 , vol. 47, # 27 p. 6749 - 6759
反应条件
1: 78 percent / PCl3 / CHCl3
2: 85 percent / methanol / 2 h / Heating
View Scheme
参考文献
Trecourt, Francois; Queguiner, Guy
Journal of Chemical Research, Miniprint, 1982 , # 3 p. 912 - 942
