2,2-二甲基环丙烷羧酸乙酯合成路线 （共 5 条）
反应条件
ammonia; sodium methylate in methanol; formamide T=80°C; P=1500.15 Torr; 5 h; Inert atmosphere; Concentration;
参考文献
SUMITOMO CHEMICAL COMPANY, LIMITED; Tomokawa, Junichi; Kimura, Takahiro; Hirata, Norihiko
Patent: US2013/123505 A1, 2013 ;
Location in patent: Paragraph 0066 ;
反应条件
potassium hydroxide in methanol
参考文献
Julia,M. et al.
Bulletin de la Societe Chimique de France, 1961 , p. 1857 - 1860
反应条件
1: (i) LiAlH4, Et2O, (ii) H2O
2: CrO3, Py / CH2Cl2
3: (i) nBuLi, THF, (ii) /BRN= 2037512/
View Scheme
参考文献
Salomon,R.G. et al.
Journal of Organic Chemistry, 1975 , vol. 40, # 6 p. 756 - 760
反应条件
(i) LiAlH4, Et2O, (ii) H2O; Multistep reaction;
参考文献
Salomon,R.G. et al.
Journal of Organic Chemistry, 1975 , vol. 40, # 6 p. 756 - 760
反应条件
(i) NaNO2, NaOAc, AcOH, (ii) (irradiation); Multistep reaction;
参考文献
Schoellkopf,U. et al. Justus Liebigs Annalen der Chemie, 1969 , vol. 730, p. 1 - 15
